2021 – Active components of Bupleurum chinense and Angelica biserrata showed analgesic effects in formalin induced pain by acting on NaV1.7

Ethnopharmacology relevance – Pain is an unpleasant sensory and emotional experience, often accompanied by the occurrence of a variety of diseases. More than 800 kinds of traditional Chinese medicines (TCM) has now been reported for pain relief and several monomers have been developed into novel analgesic drugs. Bupleurum chinense and Angelica biserrata were representatives of the TCM that are currently available for the treatment of pain.