Patchliner – Dr. Carol Milligan

An amazingly versatile platform for all your electrophysiological needs. Our research focuses on understanding the pathology of ion channel disorders, using in vitro and in vivo electrophysiology to reveal opportunities for developing novel therapies. In particular, our research focuses on ion channel gene mutations that cause epilepsy. Patchliner has been an invaluable tool enabling us to examine ion channels both endogenously and exogenously expressed by a variety of different cell types, including mammalian cell lines as well as primary cells. The system allows us to examine the effects of different mutations and different compounds on the biophysical properties of a variety of ion channels, including sodium, potassium and calcium, to mention a few. Patchliner produces high fidelity, reproducible data which is very comparable to that produced using conventional techniques. It is easy to use and throughput is an attractive bonus. The systems temperature control is a really great feature for temperature sensitive channels. The after sales service from this company is second to none.