We originally acquired a SyncroPatch 384PE in 2014 (later upgraded to 768PE) and enjoyed amazing success using it for a variety of in vitro studies of human ion channel variants. The Nanion team provided amazing support during these early years who operated more like a scientific collaborator than an instrument supplier. However, this legacy instrument was not equipped for performing current clamp recording and our research evolved to need this feature.
Fortunately for us, Nanion provided a loaner SyncroPatch 384 in April 2021 to allow us opportunities to generate action potential recordings from human iPSC-derived cardiomyocytes and some mouse neuron preparations. These preliminary data solidified our competitiveness for an NIH shared instrument grant to purchase the instrument, which was funded after only one submission. The chance to ‘test drive’ the new SyncroPatch 384 was transformative for our research and helped us acquire needed funding to purchase the instrument. Nanion is great scientific partner.