{"id":3473,"date":"2023-02-17T07:09:33","date_gmt":"2023-02-17T07:09:33","guid":{"rendered":"http:\/\/ionchanneltargets.com\/resource_library\/cardioexcyte-96-flexcyte-96-product-flyer-plates\/"},"modified":"2023-02-17T07:09:34","modified_gmt":"2023-02-17T07:09:34","slug":"2003-charge-displacements-during-atp-hydrolysis-and-synthesis-of-the-na-transporting-fof1-atpase-of-ilyobacter-tartaricus","status":"publish","type":"resource_library","link":"https:\/\/nanion.com\/zh-hans\/resource_library\/2003-charge-displacements-during-atp-hydrolysis-and-synthesis-of-the-na-transporting-fof1-atpase-of-ilyobacter-tartaricus\/","title":{"rendered":"2003 &#8211; Charge displacements during ATP-hydrolysis and synthesis of the Na<sup>+<\/sup>-transporting FoF1-ATPase of Ilyobacter tartaricus"},"content":{"rendered":"<p>Transient electrical currents generated by the Na<sup>+<\/sup>-transporting FoF1-ATPase of Ilyobacter tartaricus were observed in the hydrolytic and synthetic mode of the enzyme. Two techniques were applied: a photochemical ATP concentration jump on a planar lipid membrane and a rapid solution exchange on a solid supported membrane. We have identified an electrogenic reaction in the reaction cycle of the FoF1-ATPase that is related to the translocation of the cation through the membrane bound Fo\u00a0subcomplex of the ATPase. In addition, we have determined rate constants for the process: For ATP hydrolysis this reaction has a rate constant of 15\u201330\u2005s\u22121 if H+\u00a0is transported and 30\u201360\u2005s\u22121\u00a0if Na<sup>+<\/sup> is transported. For ATP synthesis the rate constant is 50\u201370\u2005s\u22121.<\/p>\n","protected":false},"featured_media":0,"template":"","products_tags":[36],"resource_type":[75],"application_areas":[108],"therapeutic_areas":[],"target_categories":[60],"target_families":[353],"targets":[210],"resource_keyword":[],"class_list":["post-3473","resource_library","type-resource_library","status-publish","hentry","products_tags-surfe2r-n1","resource_type-publication","application_areas-transporters","target_categories-transporters","target_families-f-type-atpases","targets-fof1-atpase"],"acf":[],"_links":{"self":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_library\/3473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_library"}],"about":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/types\/resource_library"}],"wp:attachment":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=3473"}],"wp:term":[{"taxonomy":"products_tags","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/products_tags?post=3473"},{"taxonomy":"resource_type","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_type?post=3473"},{"taxonomy":"application_areas","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/application_areas?post=3473"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/therapeutic_areas?post=3473"},{"taxonomy":"target_categories","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/target_categories?post=3473"},{"taxonomy":"target_families","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/target_families?post=3473"},{"taxonomy":"targets","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/targets?post=3473"},{"taxonomy":"resource_keyword","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_keyword?post=3473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}