{"id":16869,"date":"2025-02-11T14:25:36","date_gmt":"2025-02-11T14:25:36","guid":{"rendered":"https:\/\/www.nanion.de\/?post_type=resource_library&#038;p=16869"},"modified":"2025-02-20T18:15:03","modified_gmt":"2025-02-20T18:15:03","slug":"nav-1-7-nachr-toxin-block-of-nav1-7-and-nachr-receptors-on-the-patchliner","status":"publish","type":"resource_library","link":"https:\/\/nanion.com\/zh-hans\/resource_library\/nav-1-7-nachr-toxin-block-of-nav1-7-and-nachr-receptors-on-the-patchliner\/","title":{"rendered":"Na<sub>V<\/sub> 1.7, nAChR &#8211; &#8220;Toxin block of NaV1.7 and nAChR  receptors on the Patchliner&#8221;"},"content":{"rendered":"<p>Traditional drug development for ion channels has predominantly focused on small molecules. While effective, this approach often encounters challenges, particularly with selectivity and safety. Biologics, including toxins and venom-derived peptides, have emerged as a promising alternative to address these limitations. Animal toxins have long been invaluable in ion channel research, offering insights into their structure, function, and gating mechanisms. Venoms are now recognized as a rich resource for innovative research tools and therapeutic leads. Peptide-based drugs, derived from these venoms, have gained attention for their unique advantages, such as larger interaction surfaces that confer greater specificity and selectivity compared to small molecules.<\/p>\n","protected":false},"featured_media":0,"template":"","products_tags":[44],"resource_type":[90],"application_areas":[50,53,99],"therapeutic_areas":[143,290],"target_categories":[61],"target_families":[332],"targets":[116],"resource_keyword":[],"class_list":["post-16869","resource_library","type-resource_library","status-publish","hentry","products_tags-patchliner","resource_type-application-note","application_areas-ion-channels","application_areas-assay-development-and-validation","application_areas-pores-and-toxins","therapeutic_areas-assay-development-and-validation","therapeutic_areas-toxicology","target_categories-voltage-gated-ion-channels","target_families-nav-channels","targets-nav1-7"],"acf":[],"_links":{"self":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_library\/16869","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_library"}],"about":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/types\/resource_library"}],"wp:attachment":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=16869"}],"wp:term":[{"taxonomy":"products_tags","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/products_tags?post=16869"},{"taxonomy":"resource_type","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_type?post=16869"},{"taxonomy":"application_areas","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/application_areas?post=16869"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/therapeutic_areas?post=16869"},{"taxonomy":"target_categories","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/target_categories?post=16869"},{"taxonomy":"target_families","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/target_families?post=16869"},{"taxonomy":"targets","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/targets?post=16869"},{"taxonomy":"resource_keyword","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/resource_keyword?post=16869"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}