{"id":16519,"date":"2024-11-26T14:36:14","date_gmt":"2024-11-26T14:36:14","guid":{"rendered":"https:\/\/www.nanion.de\/?post_type=products&#038;p=16519"},"modified":"2025-01-16T11:13:33","modified_gmt":"2025-01-16T11:13:33","slug":"contractility-under-physiological-conditions","status":"publish","type":"products","link":"https:\/\/nanion.com\/zh-hans\/products\/contractility-under-physiological-conditions\/","title":{"rendered":"Contractility under physiological conditions"},"content":{"rendered":"<div id=\"pl-16519\" class=\"panel-layout\"><div id=\"pg-16519-0\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-16519-0\"><div id=\"pgc-16519-0-0\" class=\"panel-grid-cell panel-grid-cell-mobile-last\"><div id=\"panel-16519-0-0-0\" class=\"so-panel widget widget_characters-max-header-widget panel-first-child panel-last-child\" data-index=\"0\"><div class=\"so-widget-characters-max-header-widget so-widget-characters-max-header-widget-default-d75171398898-16519\"><div class=\"characters-max-header\">\n\t<p style=\"color: #008d97;font-size: 34px;font-weight: 700;\">] FLEXcyte 96 [<\/p><\/div><\/div><\/div><\/div><div id=\"pgc-16519-0-1\" class=\"panel-grid-cell panel-grid-cell-empty\"><div class=\"panel-cell-style panel-cell-style-for-16519-0-1\"><\/div><\/div><\/div><\/div><div id=\"pg-16519-1\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-16519-1\"><div id=\"pgc-16519-1-0\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><div id=\"pgc-16519-1-1\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-16519-1-1\"><div id=\"panel-16519-1-1-0\" class=\"so-panel widget widget_sow-image panel-first-child panel-last-child\" data-index=\"1\"><div class=\"so-widget-sow-image so-widget-sow-image-default-113ccd71f3e6-16519\">\n<div class=\"sow-image-container\">\n\t\t<noscript><img src=\"https:\/\/nanion.com\/wp-content\/uploads\/2024\/11\/FLEXcyte-96-contraction-of-membranes_short.gif\" width=\"640\" height=\"234\" sizes=\"(max-width: 640px) 100vw, 640px\" title=\"FLEXcyte 96 contraction of membranes_short\" alt class=\"so-widget-image\"><\/noscript><img src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20640%20234%22%3E%3C%2Fsvg%3E\" width=\"640\" height=\"234\" sizes=\"(max-width: 640px) 100vw, 640px\" title=\"FLEXcyte 96 contraction of membranes_short\" alt class=\"so-widget-image lazyload\" data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2024\/11\/FLEXcyte-96-contraction-of-membranes_short.gif\">\n\t<\/div>\n\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-16519-2\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-16519-2\"><div id=\"pgc-16519-2-0\" class=\"panel-grid-cell\"><div id=\"panel-16519-2-0-0\" class=\"so-panel widget widget_characters-max-header-widget panel-first-child panel-last-child\" data-index=\"2\"><div class=\"so-widget-characters-max-header-widget so-widget-characters-max-header-widget-default-d75171398898-16519\"><div class=\"characters-max-header\">\n\t<h4 style=\"color: #77c2a1;font-weight: 700;\"><\/h4><\/div><\/div><\/div><\/div><div id=\"pgc-16519-2-1\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-16519-2-1\"><div id=\"panel-16519-2-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"3\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\"><h3 class=\"widget-title\"><strong>Contractility under physiological conditions<\/strong><\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>&nbsp;<\/p>\n<p>The <a href=\"\/products\/flexcyte-96\/\">FLEXcyte&nbsp;96<\/a> brings <em>in vitr<\/em>o contraction force measurements of cardiac cells to a new dimension. By using a well-defined, flexible substrate for cardiac cells, the system leverages maturity and mature responses of stem cell-derived cardiomyocytes to pharmacological compounds in a higher throughput format. In the 96-well plate, the cells adhere as monolayers on the flexible substrates and the contractility of the synchronized cell layers is recorded.<\/p>\n<p>This unique technology allows for recordings in a native-like environment close to the mechanical conditions of the heart. The FLEXcyte&nbsp;96 is a turn-key system for structural and functional contraction force recordings in cardiotoxicity, safety and efficacy screening, and basic research.<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-16519-2-1-1\" class=\"so-panel widget widget_sow-image\" data-index=\"4\"><div class=\"so-widget-sow-image so-widget-sow-image-default-113ccd71f3e6-16519\"><\/div><\/div><div id=\"panel-16519-2-1-2\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"5\"><div class=\"so-widget-sow-button so-widget-sow-button-flat-24c0153bf600-16519\"><div class=\"ow-button-base ow-button-align-left\">\n\t\t\t<a href=\"\/request-informationflx\/\" class=\"btn-primary sf-form sowb-button ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\">\n\t\t<span>\n\t\t\t\n\t\t\tSchedule a meeting\t\t<\/span>\n\t\t\t<\/a>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-16519-3\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-16519-3\"><div id=\"pgc-16519-3-0\" class=\"panel-grid-cell\"><div id=\"panel-16519-3-0-0\" class=\"so-panel widget widget_characters-max-header-widget panel-first-child panel-last-child\" data-index=\"6\"><div class=\"so-widget-characters-max-header-widget so-widget-characters-max-header-widget-default-d75171398898-16519\"><div class=\"characters-max-header\">\n\t<h4 style=\"color: #77c2a1;font-weight: 700;\">Recommended publications<\/h4><\/div><\/div><\/div><\/div><div id=\"pgc-16519-3-1\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-16519-3-1\"><div id=\"panel-16519-3-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"7\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li>Chamber-specific contractile responses of atrial and ventricular hiPSC-cardiomyocytes to GPCR and ion channel targeting compounds: A microphysiological system for cardiac drug development <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S105687192400039X\">]&nbsp;View&nbsp;publication&nbsp;[<\/a><\/li>\n<li>Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessment <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1056871920302215?via%3Dihub\">]&nbsp;View&nbsp;publication&nbsp;[<\/a><\/li>\n<li>Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation <a href=\"https:\/\/www.jove.com\/t\/64283\/hybrid-cell-analysis-system-to-assess-structural-contractile-changes\">]&nbsp;View&nbsp;publication&nbsp;[<\/a>\n<p>&nbsp;<\/p>\n<\/li>\n<\/ul>\n<p><a href=\"\/products\/flexcyte-96\/resources\/?_sft_products_tags=flexcyte-96\">] Discover more [<\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-16519-4\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-16519-4\"><div id=\"pgc-16519-4-0\" class=\"panel-grid-cell\"><div id=\"panel-16519-4-0-0\" class=\"so-panel widget widget_characters-max-header-widget panel-first-child panel-last-child\" data-index=\"8\"><div class=\"so-widget-characters-max-header-widget so-widget-characters-max-header-widget-default-d75171398898-16519\"><div class=\"characters-max-header\">\n\t<h4 style=\"color: #77c2a1;font-weight: 700;\">Advance your cardiac research<\/h4><\/div><\/div><\/div><\/div><div id=\"pgc-16519-4-1\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-16519-4-1\"><div id=\"panel-16519-4-1-0\" class=\"so-panel widget widget_media_video panel-first-child panel-last-child\" data-index=\"9\"><div style=\"width:100%;\" class=\"wp-video\"><video class=\"wp-video-shortcode\" id=\"video-16519-1\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Flexcyte-96_480p.mp4?_=1\"><source type=\"video\/mp4\" src=\"\/wp-content\/uploads\/2023\/01\/Flexcyte-96_480p.mp4?_=1\"><a href=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Flexcyte-96_480p.mp4\">https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Flexcyte-96_480p.mp4<\/a><\/video><\/div><\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>] FLEXcyte 96 [ Contractility under physiological condi [&hellip;]<\/p>\n","protected":false},"featured_media":0,"parent":0,"menu_order":80,"template":"","product_categories":[],"class_list":["post-16519","products","type-products","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/products\/16519","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/products"}],"about":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/types\/products"}],"wp:attachment":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=16519"}],"wp:term":[{"taxonomy":"product_categories","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/product_categories?post=16519"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}