{"id":17133,"date":"2025-04-10T15:41:18","date_gmt":"2025-04-10T15:41:18","guid":{"rendered":"https:\/\/www.nanion.de\/?post_type=news&#038;p=17133"},"modified":"2025-05-26T18:07:18","modified_gmt":"2025-05-26T18:07:18","slug":"webinar-apc-for-enhanced-variant-assessment-in-cardiac-channelopathies","status":"publish","type":"news","link":"https:\/\/nanion.com\/zh-hans\/news\/webinar-apc-for-enhanced-variant-assessment-in-cardiac-channelopathies\/","title":{"rendered":"Webinar: APC for enhanced variant assessment in cardiac channelopathies"},"content":{"rendered":"<div id=\"pl-17133\" class=\"panel-layout\"><div id=\"pg-17133-0\" class=\"panel-grid panel-no-style\"><div id=\"pgc-17133-0-0\" class=\"panel-grid-cell\"><div id=\"panel-17133-0-0-0\" class=\"so-panel widget widget_text panel-first-child\" data-index=\"0\">\t\t\t<div class=\"textwidget\"><h4>Available on-demand. Watch now!<\/h4>\n<\/div>\n\t\t<\/div><div id=\"panel-17133-0-0-1\" class=\"so-panel widget widget_vido-lightbox-theme-widget\" data-index=\"1\"><div class=\"so-widget-vido-lightbox-theme-widget so-widget-vido-lightbox-theme-widget-default-d75171398898-17133\"><div class=\"video-lightbox\">\n                <div class=\"image\">\n                <div class=\"play-button\"><a href=\"https:\/\/youtu.be\/U5snMQKtmzY\" data-fancybox data-scrolling=\"no\"><\/a><\/div>\n                <noscript><img decoding=\"async\" width=\"2560\" height=\"1340\" src=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-scaled.png\" class=\"attachment-full size-full\" alt srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-scaled.png 2560w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-300x157.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-1024x536.png 1024w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-768x402.png 768w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-1536x804.png 1536w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-2048x1072.png 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\"><\/noscript><img decoding=\"async\" width=\"2560\" height=\"1340\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%202560%201340%22%3E%3C%2Fsvg%3E\" class=\"attachment-full size-full lazyload\" alt srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%202560%201340%22%3E%3C%2Fsvg%3E 2560w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" data-srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-scaled.png 2560w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-300x157.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-1024x536.png 1024w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-768x402.png 768w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-1536x804.png 1536w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-2048x1072.png 2048w\" data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-_APC-for-enhanced-variant-assesment-in-cardiac-channelopathies-with-Chai-Ann-Ng_ON-DEMAND-scaled.png\">            <\/div>\n        <\/div><\/div><\/div><div id=\"panel-17133-0-0-2\" class=\"so-panel widget widget_sow-editor\" data-index=\"2\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h4>Do you have any questions about the webinar?<\/h4>\n<h4>Feel free to reach out to us!<\/h4>\n<\/div>\n<\/div><\/div><div id=\"panel-17133-0-0-3\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"3\"><div class=\"so-widget-sow-button so-widget-sow-button-flat-24c0153bf600-17133\"><div class=\"ow-button-base ow-button-align-left\">\n\t\t\t<a href=\"mailto:team.marketing@nanion.de\" class=\"btn-primary sf-form sowb-button ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\">\n\t\t<span>\n\t\t\t\n\t\t\tContact us\t\t<\/span>\n\t\t\t<\/a>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-17133-1\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-17133-1\"><div id=\"pgc-17133-1-0\" class=\"panel-grid-cell\"><div id=\"panel-17133-1-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"4\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h4 data-start=\"351\" data-end=\"455\"><strong>Join us to learn how Automated Patch Clamp (APC) supports enhanced variant assessment in cardiac channelopathies<\/strong><\/h4>\n<p class data-start=\"568\" data-end=\"806\">Most missense variants are classified as Variants of Uncertain Significance (VUS) due to lack of evidence. A VUS finding is medically unactionable, which hinders cascade testing, family planning, and the practice of precision medicine.<\/p>\n<p class data-start=\"761\" data-end=\"1227\">In this webinar, <a href=\"https:\/\/www.victorchang.edu.au\/about-us\/our-scientists\/dr-chaiann-ng\">Dr. Chai (Andy) Ng<\/a> from the Victor Chang Cardiac Research Institute (member of Prof. Jamie Vandenberg\u2019s lab) will explain how calibrated high-throughput patch-clamp assays using population variant controls can provide validated functional evidence to support the pathogenicity of variants detected in patients with inherited heart diseases such as long QT and Brugada syndromes. He will also discuss how these data can be used to estimate risk and penetrance.<\/p>\n<p class data-start=\"1229\" data-end=\"1353\">If you would like to learn more about the relevant work carried out in the lab of Jamie Vandenberg, please visit: <a href=\"https:\/\/www.victorchang.edu.au\/about-us\/our-scientists\/prof-jamie-vandenberg\">Professor Jamie Vandenberg - Victor Chang Cardiac Research Institute<\/a><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-17133-1-0-1\" class=\"so-panel widget widget_sow-editor\" data-index=\"5\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h4 data-start=\"1389\" data-end=\"1403\"><strong data-start=\"1393\" data-end=\"1403\">Agenda<\/strong><\/h4>\n<ul data-start=\"1404\" data-end=\"1560\">\n<li class data-start=\"1404\" data-end=\"1456\">\n<p class data-start=\"1406\" data-end=\"1456\"><strong data-start=\"1406\" data-end=\"1432\">Welcome &amp; Introduction<\/strong> (Nanion Technologies)<\/p>\n<\/li>\n<li class data-start=\"1457\" data-end=\"1517\">\n<p class data-start=\"1459\" data-end=\"1517\"><strong data-start=\"1459\" data-end=\"1477\">Featured talk: <\/strong>\"Automated Patch Clamp for Enhanced Variant Assessment in Cardiac Channelopathies: Improving Classification, and Estimation of Penetrance\" by <em>Dr. Chai-Ann Ng, Senior Staff Scientist at Victor Chang Cardiac Research Institute<\/em><\/p>\n<\/li>\n<li class data-start=\"1518\" data-end=\"1560\">\n<p class data-start=\"1520\" data-end=\"1560\"><strong data-start=\"1520\" data-end=\"1560\">Interactive discussion &amp; Q&amp;A session<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><div id=\"panel-17133-1-0-2\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"6\"><div class=\"so-widget-sow-button so-widget-sow-button-flat-24c0153bf600-17133\"><div class=\"ow-button-base ow-button-align-left\">\n\t\t\t<a href=\"https:\/\/youtu.be\/U5snMQKtmzY\" class=\"btn-primary sf-form sowb-button ow-icon-placement-left ow-button-hover\" target=\"_blank\" rel=\"noopener noreferrer\">\n\t\t<span>\n\t\t\t\n\t\t\tWatch on-demand\t\t<\/span>\n\t\t\t<\/a>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pg-17133-2\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-17133-2\"><div id=\"pgc-17133-2-0\" class=\"panel-grid-cell\"><div id=\"panel-17133-2-0-0\" class=\"so-panel widget widget_media_image panel-first-child panel-last-child\" data-index=\"7\"><noscript><img decoding=\"async\" width=\"2500\" height=\"1308\" src=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang.png\" class=\"image wp-image-17156  attachment-full size-full\" alt style=\"max-width: 100%; height: auto;\" srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang.png 2500w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-300x157.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-1024x536.png 1024w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-768x402.png 768w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-1536x804.png 1536w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-2048x1072.png 2048w\" sizes=\"(max-width: 2500px) 100vw, 2500px\"><\/noscript><img decoding=\"async\" width=\"2500\" height=\"1308\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%202500%201308%22%3E%3C%2Fsvg%3E\" class=\"image wp-image-17156  attachment-full size-full lazyload\" alt style=\"max-width: 100%; height: auto;\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%202500%201308%22%3E%3C%2Fsvg%3E 2500w\" sizes=\"(max-width: 2500px) 100vw, 2500px\" data-srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang.png 2500w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-300x157.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-1024x536.png 1024w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-768x402.png 768w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-1536x804.png 1536w, https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang-2048x1072.png 2048w\" data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2025\/04\/2025_Webinar-Chai-Ng-Victor-Chang.png\"><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Date: May 8, 2025<br \/>\nTime: 16:00 \u2013 17:00 CEST<br \/>\nLocation: Online via Zoom<\/p>\n","protected":false},"featured_media":17144,"template":"","news_categories":[528,13],"class_list":["post-17133","news","type-news","status-publish","has-post-thumbnail","hentry","news_categories-front-page-news","news_categories-event"],"acf":[],"_links":{"self":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/news\/17133","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/news"}],"about":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/types\/news"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/media\/17144"}],"wp:attachment":[{"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=17133"}],"wp:term":[{"taxonomy":"news_categories","embeddable":true,"href":"https:\/\/nanion.com\/zh-hans\/wp-json\/wp\/v2\/news_categories?post=17133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}