{"id":6764,"date":"2023-02-17T06:59:19","date_gmt":"2023-02-17T06:59:19","guid":{"rendered":"https:\/\/beta.nanion.de\/resource_library\/neurons-stem-cell-derived-neurons-recorded-on-nanions-patchliner\/"},"modified":"2023-02-17T06:59:19","modified_gmt":"2023-02-17T06:59:19","slug":"neurons-stem-cell-derived-neurons-recorded-on-nanions-patchliner","status":"publish","type":"resource_library","link":"https:\/\/nanion.com\/ja\/resource_library\/neurons-stem-cell-derived-neurons-recorded-on-nanions-patchliner\/","title":{"rendered":"Neurons &#8211; &#8220;Stem cell-derived neurons recorded on Nanion&#8217;s Patchliner&#8221;"},"content":{"rendered":"<p>Cellular Dynamics International is developing iCell<sup>\u00ae<\/sup>\u00a0Neurons, human iPS cell-derived neurons. These neurons have been used on Nanion\u2019s Patchliner, an automated patch clamp device for recording from up to 8 cells simultaneously. Cells were thawed and cultured as per the manufacturer\u2019s instructions. After plating, cells developed neuronal outgrowth within 24 hours and could be kept in culture for 2 weeks. An investigation into voltage- and ligand-gated ion channels expressed in these cells was undertaken using the Patchliner. The first experiments are shown here and offer promising results for combining a cellular model for neurons and an increased throughput patch clamp device.<\/p>\n","protected":false},"featured_media":0,"template":"","products_tags":[44],"resource_type":[90],"application_areas":[50,77],"therapeutic_areas":[55],"target_categories":[61,337],"target_families":[332,359],"targets":[116],"resource_keyword":[],"class_list":["post-6764","resource_library","type-resource_library","status-publish","hentry","products_tags-patchliner","resource_type-application-note","application_areas-ion-channels","application_areas-cell-ipscs-profiling","therapeutic_areas-cns","target_categories-voltage-gated-ion-channels","target_categories-ligand-gated-ion-channels","target_families-nav-channels","target_families-gabaa-receptors","targets-nav1-7"],"acf":[],"_links":{"self":[{"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/resource_library\/6764","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/resource_library"}],"about":[{"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/types\/resource_library"}],"wp:attachment":[{"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/media?parent=6764"}],"wp:term":[{"taxonomy":"products_tags","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/products_tags?post=6764"},{"taxonomy":"resource_type","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/resource_type?post=6764"},{"taxonomy":"application_areas","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/application_areas?post=6764"},{"taxonomy":"therapeutic_areas","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/therapeutic_areas?post=6764"},{"taxonomy":"target_categories","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/target_categories?post=6764"},{"taxonomy":"target_families","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/target_families?post=6764"},{"taxonomy":"targets","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/targets?post=6764"},{"taxonomy":"resource_keyword","embeddable":true,"href":"https:\/\/nanion.com\/ja\/wp-json\/wp\/v2\/resource_keyword?post=6764"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}