{"id":14366,"date":"2022-08-30T08:19:37","date_gmt":"2022-08-30T06:19:37","guid":{"rendered":"https:\/\/www.nanion.de\/application-areas\/drug-discovery\/"},"modified":"2025-10-23T06:51:19","modified_gmt":"2025-10-23T04:51:19","slug":"drug-discovery","status":"publish","type":"page","link":"https:\/\/nanion.com\/ja\/application-areas\/drug-discovery\/","title":{"rendered":"Drug discovery"},"content":{"rendered":"<div id=\"pl-14366\" class=\"panel-layout\"><div id=\"pg-14366-0\" class=\"panel-grid panel-has-style\"><div class=\"siteorigin-panels-stretch panel-row-style panel-row-style-for-14366-0\" data-stretch-type=\"full-width-stretch\"><div id=\"pgc-14366-0-0\" class=\"panel-grid-cell\"><div id=\"panel-14366-0-0-0\" class=\"so-panel widget widget_general-text-widget panel-first-child panel-last-child\" data-index=\"0\"><div class=\"so-widget-general-text-widget so-widget-general-text-widget-title-widget-de16310f3dd9-14366\"><style>\n    <\/style>\n<div class=\"container simple-header-section \">\n\t<div class=\"titlewidget-section\" uk-scrollspy=\"cls:uk-animation-slide-bottom; delay: 300\">\n\t\t<svg class=\"bf-text-mobile\">\t\n\t\t\t<path class=\"st0\" d=\"M8.6,104.7V16.3H0V0h26v9.5v6.7v88.4v4.4v11.9H0v-16.3H8.6z\" \/>\n\t\t<\/svg>\n\n\t\t<svg class=\"bf-text\">\n\t\t\t<path d=\"M0.5,0.3V23h12v123h-12v22.7h36.3v-16.5V146V23v-9.4V0.3H0.5z\" \/>\n\t\t<\/svg>\n\t\t\n\t\t<div class=\"title-box\">\n\t\t\t\t\t\t\n\t\t\t\t<div class=\"texttitle\" uk-scrollspy=\"cls:uk-animation-slide-bottom; delay: 400\">\n\t\t\t\t\t<h1>Drug discovery<\/h1>\n<\/div>\n\t\t\t\t\t\t\n\n\t\t\t\t\t\t\t<h4 class=\"titledescription\" uk-scrollspy=\"cls:uk-animation-slide-bottom; delay: 500\">\n\t\t\t\t\t Search for new and better treatments.<\/h4>\n\t\t\t\n\t\t<\/div>\n\n\t\t<svg class=\"at-text\">\n\t\t\t<path d=\"M25.2,146.2V22.8h12V0H0.8v13.3v9.4v123.5v6.2V169h36.3v-22.8H25.2z\" \/>\n\t\t\t<\/svg>\n\t\t\n\t\t<svg class=\"at-text-mobile\">\t\n\t\t\t<path class=\"st0\" d=\"M17.4,104.7V16.3H26V0H0v9.5v6.7v88.4v4.4v11.9h26v-16.3H17.4z\" \/>\n\t\t<\/svg>\n\t<\/div>\n    <\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-14366-1\" class=\"panel-grid panel-has-style\"><div class=\"bg-right panel-row-style panel-row-style-for-14366-1\"><div id=\"pgc-14366-1-0\" class=\"panel-grid-cell\"><div id=\"panel-14366-1-0-0\" class=\"so-panel widget widget_read-more-widget panel-first-child panel-last-child\" data-index=\"1\"><div class=\"white-text panel-widget-style panel-widget-style-for-14366-1-0-0\"><div class=\"so-widget-read-more-widget so-widget-read-more-widget-default-d75171398898-14366\"><style>\n    \/*.read-more-section .image-wrapper #box-img-1884391749{\n        width: ;\n        height: ;\n    }*\/\n    .read-more-section .image-wrapper #box-img-1884391749 .image{\n        width: calc(100% + );\n        height: calc(100% + );\n    }\n<\/style>\n<div class=\"read-more-section row\" id=\"readmore-1593260382\">\n                            <div class=\"col-12 col-md-4 image-wrapper order-0\"> <!--data-aos=\"fade-down\" data-aos-offset=\"700\" data-aos-duration=\"5000\" data-aos-once=\"true\"-->\n                        <div class=\"box-img\" id=\"box-img-1884391749\" data-mark>\n                            <noscript><img decoding=\"async\" class=\"image\" src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/22E4050w.jpg\" style><\/noscript><img decoding=\"async\" class=\"image lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" style data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/22E4050w.jpg\">\n                        <\/div>\n                <\/div>\n                    <div class=\"col-12 col-md-8 text-wrapper order-1\">\n        <div class=\"title\">\n            <h2><strong>From Molecules to Medicine:<\/strong> A Journey of Drug Discovery<\/h2>\n        <\/div>\n                    <div class=\"description focus-description \">\n                <p>Drug discovery is a complex and expensive process, with 1% of new candidates making it to market at a cost of billions for each new drug. Drug attrition can result from safety issues, poor efficacy or translation from preclinical models to human patients, clinical trial costs, and market competition. Drug discovery is typically done by pharmaceutical companies and biotechs, but now disease and patient foundations and charities are supporting drug discovery for rare and common diseases, and academics are identifying new drugs or carrying out clinical trials. Cancer remains the main area of drug discovery, followed by neuroscience, metabolic disease, and cardiac ailments.<\/p>\n            <\/div>\n            \n    <\/div>\n<\/div>\n\n<script>\n    jQuery(document).ready(function($){\n        jQuery('.read-more-section a[href^=\"tel:\"]').addClass('no-underline');\n\n        if($(document).width() <= 992){\n            let imgHeight = $(\"#readmore-1593260382 .image-wrapper >.box-img\").height();\n            readMoreSetMgB(imgHeight);\n        }else{\n            readMoreSetMgB(0);\n        }\n        $(window).resize(function(){\n            if($(document).width() <= 992){\n                let imgHeight = $(\"#readmore-1593260382 .image-wrapper >.box-img\").height();\n                readMoreSetMgB(imgHeight);\n            }else{\n                readMoreSetMgB(0);\n            }\n        })\n\n        function readMoreSetMgB(imgHeight){\n            \/*console.log('height '+imgHeight);*\/\n            if(imgHeight > 0){\n                $(\"#readmore-1593260382\").closest('.panel-grid').css('margin-bottom',(imgHeight)+'px');\n            }else{\n                $(\"#readmore-1593260382\").closest('.panel-grid').css('margin-bottom','');\n            }\n        }\n    });\n\n<\/script>\n<\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-14366-2\" class=\"panel-grid panel-no-style\"><div id=\"pgc-14366-2-0\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><div id=\"pgc-14366-2-1\" class=\"panel-grid-cell\"><div id=\"panel-14366-2-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"2\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h2><strong>Drug discovery screening<\/strong><\/h2>\n<h2>cascade and workflow<\/h2>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-14366-3\" class=\"panel-grid panel-no-style\"><div id=\"pgc-14366-3-0\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-14366-3-0\"><div id=\"panel-14366-3-0-0\" class=\"so-panel widget widget_sow-headline panel-first-child panel-last-child\" data-index=\"3\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-14366-3-0-0\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-f63c946382f4-14366\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h4 class=\"sow-headline\">\n\t\t\t\t\t\tThe drug discovery process \t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pgc-14366-3-1\" class=\"panel-grid-cell panel-grid-cell-mobile-last\"><div id=\"panel-14366-3-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"4\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Drug discovery is a long process which can be divided into different phases. These range from early drug discovery which includes target identification and validation, compound screening, and lead optimization, through pre-clinical research to establish safety and efficacy, and finally clinical testing and regulatory approval. The process can take 12-15 years per new drug molecule and is costly. New small molecules are typically identified by high throughput screening (HTS) of large libraries containing millions of compounds, with hit compounds optimized by medicinal chemistry methods. Artificial intelligence (AI) and machine learning algorithms are key developments in drug discovery, to help design and optimize new molecules, predict protein shapes, interpret complex responses in phenotypic assays, and deconvolve genetic pathways. The availability of high-resolution cryo-EM protein structures and drug-binding sites facilitates structure-based drug design. Finally, a better translation of preclinical drug candidates to the clinic is possible using human patients and disease iPSC 2D cultures and 3D organoids, and the availability of human donor tissue. This also raises the possibility of personalized medicine, to identify patient-specific drug regimes.<\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-14366-3-2\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><\/div><div id=\"pg-14366-4\" class=\"panel-grid panel-no-style\"><div id=\"pgc-14366-4-0\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-14366-4-0\"><div id=\"panel-14366-4-0-0\" class=\"so-panel widget widget_sow-headline panel-first-child panel-last-child\" data-index=\"5\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-14366-4-0-0\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-f63c946382f4-14366\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h4 class=\"sow-headline\">\n\t\t\t\t\t\tNanion instruments used in drug discovery\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pgc-14366-4-1\" class=\"panel-grid-cell panel-grid-cell-mobile-last\"><div id=\"panel-14366-4-1-0\" class=\"so-panel widget widget_sow-image panel-first-child panel-last-child\" data-index=\"6\"><div class=\"so-widget-sow-image so-widget-sow-image-default-334eeca80698-14366\">\n<div class=\"sow-image-container\">\n\t\t\t<a href=\"\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_.png\" target=\"_blank\" rel=\"noopener noreferrer\">\n\t\t\t<noscript><img src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_.png\" width=\"4961\" height=\"3508\" srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_.png 4961w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-300x212.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-1024x724.png 1024w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-768x543.png 768w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-1536x1086.png 1536w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-2048x1448.png 2048w\" sizes=\"(max-width: 4961px) 100vw, 4961px\" title=\"Nanion_Drug Discovery Pipeline Overview_\" alt class=\"so-widget-image\"><\/noscript><img src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%204961%203508%22%3E%3C%2Fsvg%3E\" width=\"4961\" height=\"3508\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%204961%203508%22%3E%3C%2Fsvg%3E 4961w\" sizes=\"(max-width: 4961px) 100vw, 4961px\" title=\"Nanion_Drug Discovery Pipeline Overview_\" alt class=\"so-widget-image lazyload\" data-srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_.png 4961w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-300x212.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-1024x724.png 1024w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-768x543.png 768w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-1536x1086.png 1536w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_-2048x1448.png 2048w\" data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/10\/Nanion_Drug-Discovery-Pipeline-Overview_.png\">\n\t\t\t<\/a><\/div>\n\n<\/div><\/div><\/div><div id=\"pgc-14366-4-2\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><\/div><div id=\"pg-14366-5\" class=\"panel-grid panel-no-style\"><div id=\"pgc-14366-5-0\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><div id=\"pgc-14366-5-1\" class=\"panel-grid-cell\"><div id=\"panel-14366-5-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"7\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h2><strong>Ion channels and transporters<\/strong><\/h2>\n<h2>in drug development<\/h2>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-14366-6\" class=\"panel-grid panel-no-style\"><div id=\"pgc-14366-6-0\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-14366-6-0\"><div id=\"panel-14366-6-0-0\" class=\"so-panel widget widget_sow-headline panel-first-child panel-last-child\" data-index=\"8\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-14366-6-0-0\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-f63c946382f4-14366\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h4 class=\"sow-headline\">\n\t\t\t\t\t\tThe drug discovery process \t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pgc-14366-6-1\" class=\"panel-grid-cell panel-grid-cell-mobile-last\"><div id=\"panel-14366-6-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"9\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Ion channels have enormous potential as drug targets, whereby nearly 18% of <a href=\"https:\/\/www.ionchannellibrary.com\/ion-channel-drugs\/#Ion-channel-drugs-on-the-market\" target=\"_blank\" rel=\"noopener\">drugs on the market<\/a> today target ion channels to exert their therapeutic effects. Also, there are &gt;80 <a href=\"https:\/\/www.ionchannellibrary.com\/ion-channel-drugs\/#Ion-channel-drug-candidates-in-preclinical-development-and-clinical-trials\" target=\"_blank\" rel=\"noopener\">drug candidates<\/a> that are currently in preclinical development and clinical trials. These include P2X3 inhibitors to treat chronic cough, and NMDA receptor antagonists to treat depression. Membrane transporters are also potential therapeutic targets to treat neurological disorders and diseases such as cystic fibrosis, but should also be taken into account during the drug development process as they can play a major role in drug safety and efficacy.<\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-14366-6-1-1\" class=\"so-panel widget widget_sow-button panel-last-child\" data-index=\"10\"><div class=\"so-widget-sow-button so-widget-sow-button-flat-10f3526e3813-14366\"><div class=\"ow-button-base ow-button-align-left\">\n\t\t\t<a href=\"https:\/\/nanion.com\/resources\/target-database\/\" class=\"btn-primary sowb-button ow-icon-placement-left ow-button-hover\">\n\t\t<span>\n\t\t\t\n\t\t\tTarget database\t\t<\/span>\n\t\t\t<\/a>\n\t<\/div>\n<\/div><\/div><\/div><div id=\"pgc-14366-6-2\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><\/div><div id=\"pg-14366-7\" class=\"panel-grid panel-no-style\"><div id=\"pgc-14366-7-0\" class=\"panel-grid-cell\"><div 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id=\"panel-2409-1-0-1\" class=\"so-panel widget widget_sow-headline\" data-index=\"2\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-2409-1-0-1\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-c0a5ad089308-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h3 class=\"sow-headline\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/product_categories\/automated-patch-clamp\">\n\t\t\t\t\t\t\t\tAutomated <br>patch clamp<\/a>\t\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><div id=\"panel-2409-1-0-2\" class=\"so-panel widget widget_sow-headline\" data-index=\"3\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-2409-1-0-2\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-bfd9fd8b652a-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<p class=\"sow-headline\">\n\t\t\t\t\t\tGo directly to the product \/ technology:\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"decoration\">\n\t\t\t\t\t\t<div class=\"decoration-inside\"><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><div id=\"panel-2409-1-0-3\" class=\"so-panel widget widget_siteorigin-panels-builder panel-last-child\" data-index=\"4\"><div id=\"pl-w699872aacd312\" class=\"panel-layout\"><div id=\"pg-w699872aacd312-0\" class=\"panel-grid panel-no-style\"><div id=\"pgc-w699872aacd312-0-0\" class=\"panel-grid-cell\"><div id=\"panel-w699872aacd312-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><a class=\"font-weight-normal\" href=\"\/products\/port-a-patch\/\">Port-a-Patch<\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/patchlinere\/\">Patchliner<sup>e<\/sup><\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/syncropatch-384\/\">SyncroPatch 384<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-w699872aacd312-0-1\" class=\"panel-grid-cell\"><div id=\"panel-w699872aacd312-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><a class=\"font-weight-normal\" href=\"\/products\/port-a-patch-mini\/\">Port-a-Patch mini<\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/patchlinerm\/\">Patchliner<sup>m<\/sup><\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/buffer-solutions\/\">Buffer solutions<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pgc-2409-1-1\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-2409-1-1\"><div id=\"panel-2409-1-1-0\" class=\"so-panel widget widget_image-out-container-theme-widget panel-first-child\" data-index=\"5\"><div class=\"so-widget-image-out-container-theme-widget so-widget-image-out-container-theme-widget-default-d75171398898-1610\">    <div class=\"img-out-container-warp\" style=\"max-width:90%;position:relative;transform: translateX(-0px); float:left; left:0; z-index: 10;\">\n        <style>.lazy-loader-background-element-2.lazyloaded{ background-image: url('https:\/\/nanion.com\/wp-content\/uploads\/2022\/11\/Dotted-grid.svg') !important; }<\/style><noscript><style>.lazy-loader-background-element-2.lazyload{ background-image: url('https:\/\/nanion.com\/wp-content\/uploads\/2022\/11\/Dotted-grid.svg') !important; }<\/style><\/noscript><div class=\"dotted-grid top-right mobile-disable-dotted-grid-aimation  lazyload lazy-loader-background-element-2 \" data-translatemarky=\"-154\" data-translatemarkx=\"150\" data-duration=\"180%\" data-mobilemargin=\"no\" style=\"width:200px;height:200px; max-width:100%;\"><\/div>        <div class=\"img-out-container\">\n                                <a href=\"\/product_categories\/membrane-biophysics\">\n                        <noscript><img decoding=\"async\" width=\"782\" height=\"546\" src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697.png\" class=\"attachment-full size-full\" alt srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697.png 782w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697-300x209.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697-768x536.png 768w\" sizes=\"(max-width: 782px) 100vw, 782px\"><\/noscript><img decoding=\"async\" width=\"782\" height=\"546\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20782%20546%22%3E%3C%2Fsvg%3E\" class=\"attachment-full size-full lazyload\" alt srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20782%20546%22%3E%3C%2Fsvg%3E 782w\" sizes=\"(max-width: 782px) 100vw, 782px\" data-srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697.png 782w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697-300x209.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697-768x536.png 768w\" data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Membrane-Biophysics-Illustration-697.png\">                    <\/a>\n                            <\/div>\n                            <\/div>\n    <\/div><\/div><div id=\"panel-2409-1-1-1\" class=\"so-panel widget widget_sow-headline\" data-index=\"6\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-2409-1-1-1\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-a6aebc6e5f56-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h3 class=\"sow-headline\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/product_categories\/membrane-biophysics\">\n\t\t\t\t\t\t\t\tMembrane <br>biophysics<\/a>\t\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><div id=\"panel-2409-1-1-2\" class=\"so-panel widget widget_sow-headline\" data-index=\"7\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-2409-1-1-2\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-bfd9fd8b652a-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<p class=\"sow-headline\">\n\t\t\t\t\t\tGo directly to the product \/ technology:\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"decoration\">\n\t\t\t\t\t\t<div class=\"decoration-inside\"><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><div id=\"panel-2409-1-1-3\" class=\"so-panel widget widget_siteorigin-panels-builder panel-last-child\" data-index=\"8\"><div id=\"pl-w6998600331bfa\" class=\"panel-layout\"><div id=\"pg-w6998600331bfa-0\" class=\"panel-grid panel-no-style\"><div id=\"pgc-w6998600331bfa-0-0\" class=\"panel-grid-cell\"><div id=\"panel-w6998600331bfa-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><a class=\"font-weight-normal\" href=\"\/products\/orbit-16\/\">Orbit 16 TC<\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/surfe2r-n1\/\">SURFE<sup>2<\/sup>R N1<\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/vesicle-prep-pro\/\">Vesicle Prep Pro<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-w6998600331bfa-0-1\" class=\"panel-grid-cell\"><div id=\"panel-w6998600331bfa-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><a class=\"font-weight-normal\" href=\"\/products\/orbit-mini\/\">Orbit mini<\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/surfer-96se\/\">SURFE<sup>2<\/sup>R 96SE<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pgc-2409-1-2\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-2409-1-2\"><div id=\"panel-2409-1-2-0\" class=\"so-panel widget widget_image-out-container-theme-widget panel-first-child\" data-index=\"9\"><div class=\"so-widget-image-out-container-theme-widget so-widget-image-out-container-theme-widget-default-d75171398898-1610\">    <div class=\"img-out-container-warp\" style=\"max-width:90%;position:relative;transform: translateX(-0px); float:left; left:0; z-index: 10;\">\n        <style>.lazy-loader-background-element-3.lazyloaded{ background-image: url('https:\/\/nanion.com\/wp-content\/uploads\/2022\/11\/Dotted-grid-1.svg') !important; }<\/style><noscript><style>.lazy-loader-background-element-3.lazyload{ background-image: url('https:\/\/nanion.com\/wp-content\/uploads\/2022\/11\/Dotted-grid-1.svg') !important; }<\/style><\/noscript><div class=\"dotted-grid top-right mobile-disable-dotted-grid-aimation  lazyload lazy-loader-background-element-3 \" data-translatemarky=\"-154\" data-translatemarkx=\"150\" data-duration=\"180%\" data-mobilemargin=\"no\" style=\"width:200px;height:200px; max-width:100%;\"><\/div>        <div class=\"img-out-container\">\n                                <a href=\"\/product-categories\/cell-analytics\/\">\n                        <noscript><img decoding=\"async\" width=\"782\" height=\"546\" src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648.png\" class=\"attachment-full size-full\" alt srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648.png 782w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648-300x209.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648-768x536.png 768w\" sizes=\"(max-width: 782px) 100vw, 782px\"><\/noscript><img decoding=\"async\" width=\"782\" height=\"546\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20782%20546%22%3E%3C%2Fsvg%3E\" class=\"attachment-full size-full lazyload\" alt srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%20782%20546%22%3E%3C%2Fsvg%3E 782w\" sizes=\"(max-width: 782px) 100vw, 782px\" data-srcset=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648.png 782w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648-300x209.png 300w, https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648-768x536.png 768w\" data-src=\"https:\/\/nanion.com\/wp-content\/uploads\/2023\/01\/Cell-Monitoring-Illustration-648.png\">                    <\/a>\n                            <\/div>\n                            <\/div>\n    <\/div><\/div><div id=\"panel-2409-1-2-1\" class=\"so-panel widget widget_sow-headline\" data-index=\"10\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-2409-1-2-1\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-e546c9aa51e7-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h3 class=\"sow-headline\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/product_categories\/cell-analytics\">\n\t\t\t\t\t\t\t\tCell <br>analytics<\/a>\t\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><div id=\"panel-2409-1-2-2\" class=\"so-panel widget widget_sow-headline\" data-index=\"11\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-2409-1-2-2\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-bfd9fd8b652a-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<p class=\"sow-headline\">\n\t\t\t\t\t\tGo directly to the product \/ technology:\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"decoration\">\n\t\t\t\t\t\t<div class=\"decoration-inside\"><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><div id=\"panel-2409-1-2-3\" class=\"so-panel widget widget_siteorigin-panels-builder panel-last-child\" data-index=\"12\"><div id=\"pl-w64ad02c2b929f\" class=\"panel-layout\"><div id=\"pg-w64ad02c2b929f-0\" class=\"panel-grid panel-no-style\"><div id=\"pgc-w64ad02c2b929f-0-0\" class=\"panel-grid-cell\"><div id=\"panel-w64ad02c2b929f-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><a class=\"font-weight-normal\" href=\"\/products\/cardioexcyte-96\/\">CardioExcyte 96<\/a><\/li>\n<li><a class=\"font-weight-normal\" href=\"\/products\/flexcyte-96\/\">FLEXcyte 96<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-w64ad02c2b929f-0-1\" class=\"panel-grid-cell\"><div id=\"panel-w64ad02c2b929f-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><a class=\"font-weight-normal\" href=\"\/products\/atlaz\/\">AtlaZ<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div id=\"pg-14366-8\" class=\"panel-grid panel-has-style\"><div class=\"siteorigin-panels-stretch panel-row-style panel-row-style-for-14366-8\" data-stretch-type=\"full\"><div id=\"pgc-14366-8-0\" class=\"panel-grid-cell\"><div class=\"panel-cell-style panel-cell-style-for-14366-8-0\"><div id=\"panel-14366-8-0-0\" class=\"so-panel widget widget_sow-headline panel-first-child panel-last-child\" data-index=\"12\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-14366-8-0-0\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-f63c946382f4-1610\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h4 class=\"sow-headline\">\n\t\t\t\t\t\tDrug discovery\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pgc-14366-8-1\" class=\"panel-grid-cell panel-grid-cell-mobile-last\"><div id=\"panel-14366-8-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"13\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3><strong>Instrumentation for all phases <\/strong>of drug development<\/h3>\n<\/div>\n<\/div><\/div><div id=\"panel-14366-8-1-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"14\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>We accompany you on your drug discovery journey by providing a range of platforms for studying ion channels and membrane transporters in native and heterologous cells and membranes:<\/p>\n<ul>\n<li>Single channel recordings on&nbsp;<a href=\"\/products\/orbit-mini\/\" target=\"_blank\" rel=\"noopener\"><strong>Orbit mini<\/strong><\/a>&nbsp;and&nbsp;<a href=\"\/products\/orbit-16tc\/\" target=\"_blank\" rel=\"noopener\"><strong>Orbit 16 TC<\/strong><\/a> platforms for basic research, target discovery, and target validation.<\/li>\n<li>Whole-cell recordings on&nbsp;<a href=\"\/products\/port-a-patch\/\" target=\"_blank\" rel=\"noopener\"><strong>Port-a-Patch<\/strong><\/a>,&nbsp;<a href=\"\/products\/patchliner\/\" target=\"_blank\" rel=\"noopener\"><strong>Patchliner&nbsp;<\/strong><\/a>and&nbsp;<a href=\"\/products\/syncropatch-384\/\" target=\"_blank\" rel=\"noopener\"><strong>SyncroPatch 384<\/strong><\/a> for basic research and target discovery right through to drug screening, lead optimization, and safety testing.<\/li>\n<li>Transporter measurements on the&nbsp;<a href=\"\/products\/surfe2r-n1\/\" target=\"_blank\" rel=\"noopener\"><strong>SURFE<\/strong><strong><sup>2<\/sup><\/strong><strong>R N1<\/strong><\/a>&nbsp;and&nbsp;<a href=\"\/products\/surfer-96se\/\" target=\"_blank\" rel=\"noopener\"><strong>SURFE<\/strong><strong><sup>2<\/sup><\/strong><strong>R 96SE<\/strong><\/a> for basic research and target discovery right through to drug screening, lead optimization, and safety testing in organellar membranes.<\/li>\n<li>Contractility and field potential electrophysiology on the <a href=\"\/products\/cardioexcyte-96\/\" target=\"_blank\" rel=\"noopener\">CardioExcyte 96<\/a> and <a href=\"\/products\/flexcyte-96\/\" target=\"_blank\" rel=\"noopener\">FLEXcyte 96<\/a> for basic research and safety\/toxicology testing.<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-14366-8-2\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><\/div><\/div><div id=\"pg-14366-9\" class=\"panel-grid panel-has-style\"><div class=\"bg-left panel-row-style panel-row-style-for-14366-9\"><div id=\"pgc-14366-9-0\" class=\"panel-grid-cell\"><div id=\"panel-14366-9-0-0\" class=\"so-panel widget widget_siteorigin-panels-builder panel-first-child panel-last-child\" data-index=\"15\"><div id=\"pl-w6787aadd4ffe6\" class=\"panel-layout\"><div id=\"pg-w6787aadd4ffe6-0\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-w6787aadd4ffe6-0\"><div id=\"pgc-w6787aadd4ffe6-0-0\" class=\"panel-grid-cell\"><div id=\"panel-w6787aadd4ffe6-0-0-0\" class=\"so-panel widget widget_sow-headline panel-first-child panel-last-child\" data-index=\"0\"><div class=\"all-font-bold panel-widget-style panel-widget-style-for-w6787aadd4ffe6-0-0-0\"><div class=\"so-widget-sow-headline so-widget-sow-headline-default-087580a7c05b\"><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h2 class=\"sow-headline\">\n\t\t\t\t\t\tHow can we  help you?\t\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pgc-w6787aadd4ffe6-0-1\" class=\"panel-grid-cell panel-grid-cell-empty panel-grid-cell-mobile-last\"><\/div><div id=\"pgc-w6787aadd4ffe6-0-2\" class=\"panel-grid-cell panel-grid-cell-empty\"><\/div><\/div><\/div><div id=\"pg-w6787aadd4ffe6-1\" class=\"panel-grid panel-has-style\"><div class=\"panel-row-style panel-row-style-for-w6787aadd4ffe6-1\"><div id=\"pgc-w6787aadd4ffe6-1-0\" class=\"panel-grid-cell\"><div class=\"tablet-50 panel-cell-style panel-cell-style-for-w6787aadd4ffe6-1-0\"><div id=\"panel-w6787aadd4ffe6-1-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\"><div class=\"panel-widget-style panel-widget-style-for-w6787aadd4ffe6-1-0-0\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Contact our specialist Dr. Alison Obergrussberger (Director of Scientific Sales and Customer Engagement). Alison is delighted to help you:<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pgc-w6787aadd4ffe6-1-1\" class=\"panel-grid-cell\"><div class=\"tablet-50 panel-cell-style panel-cell-style-for-w6787aadd4ffe6-1-1\"><div id=\"panel-w6787aadd4ffe6-1-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"2\"><div class=\"panel-widget-style panel-widget-style-for-w6787aadd4ffe6-1-1-0\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><strong><a href=\"mailto:Ali.Obergrussberger@nanion.de\">Ali.Obergrussberger@nanion.de<br>\n<\/a><\/strong><br>\nor call:&nbsp;<strong>+49 89 2190 95-078<\/strong><br>\nor connect via&nbsp;<strong><a href=\"https:\/\/www.linkedin.com\/in\/ali-obergrussberger-89ba8710\/\" target=\"_blank\" rel=\"noopener\">LinkedIn<\/a><\/strong><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pgc-w6787aadd4ffe6-1-2\" 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